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DFF2 FISH Probe

The DFF2 FISH probe is designed to hybridize to the DFF2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DFFB-20-OR  (Standard Design) 20 (40 μL) 200 μL
DFFB-20-RE 20 (40 μL) 200 μL
DFFB-20-GO 20 (40 μL) 200 μL
DFFB-20-GR 20 (40 μL) 200 μL
DFFB-20-AQ 20 (40 μL) 200 μL
DFFB-20-DIG 20 (40 μL) 200 μL
DFFB-20-BIO 20 (40 μL) 200 μL

Gene Summary

Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene but the biological validity of some of these variants has not been determined. [provided by RefSeq, Sep 2013]

Gene Details

Gene Symbol: DFFB

Gene Name: DNA Fragmentation Factor Subunit Beta

Chromosome: CHR1: 3773844-3801993

Locus: 1p36.32

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DFF2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DFFB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping