DER1 FISH Probe
The DER1 FISH probe is designed to hybridize to the DER1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DERL1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DERL1-20-RE | 20 (40 μL) | 200 μL |  |
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| DERL1-20-GO | 20 (40 μL) | 200 μL |  |
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| DERL1-20-GR | 20 (40 μL) | 200 μL |  |
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| DERL1-20-AQ | 20 (40 μL) | 200 μL |  |
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| DERL1-20-DIG | 20 (40 μL) | 200 μL |  |
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| DERL1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the derlin family. Members of this family participate in the ER-associated degradation response and retrotranslocate misfolded or unfolded proteins from the ER lumen to the cytosol for proteasomal degradation. This protein recognizes substrate in the ER and works in a complex to retrotranslocate it across the ER membrane into the cytosol. This protein may select cystic fibrosis transmembrane conductance regulator protein (CFTR) for degradation as well as unfolded proteins in Alzheimer's disease. Alternative splicing results in multiple transcript variants that encode different protein isoforms. [provided by RefSeq, Aug 2012]
Gene Details
Gene Symbol: DERL1
Gene Name: Derlin 1
Chromosome: CHR8: 124025567-124054648
Locus: 8q24.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DER1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DERL1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping