DEP-1 FISH Probe
The DEP-1 FISH probe is designed to hybridize to the DEP-1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PTPRJ-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PTPRJ-20-RE | 20 (40 μL) | 200 μL |  |
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| PTPRJ-20-GO | 20 (40 μL) | 200 μL |  |
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| PTPRJ-20-GR | 20 (40 μL) | 200 μL |  |
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| PTPRJ-20-AQ | 20 (40 μL) | 200 μL |  |
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| PTPRJ-20-DIG | 20 (40 μL) | 200 μL |  |
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| PTPRJ-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: PTPRJ
Gene Name: Protein Tyrosine Phosphatase, Receptor Type J
Chromosome: CHR11: 48002109-48192394
Locus: 11p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DEP-1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PTPRJ-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping