DENND5A Break Apart FISH Probe
Empire Genomics’ DENND5A Break Apart FISH Probe is designed to flank the DENND5A gene and is typically used for detecting DENND5A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DENND5ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-GORE | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-REGO | 20 (40 μL) | 200 μL |
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| DENND5ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a DENN-domain-containing protein that functions as a RAB-activating guanine nucleotide exchange factor (GEF). This protein catalyzes the conversion of GDP to GTP and thereby converts inactive GDP-bound Rab proteins into their active GTP-bound form. The encoded protein is recruited by RAB6 onto Golgi membranes and is therefore referred to as RAB6-interacting protein 1. This protein binds with RAB39 as well. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Mutations in this gene are associated with early infantile epileptic encephalopathy-49. [provided by RefSeq, Feb 2017]
Gene Details
Gene Symbol: DENND5A
Gene Name: DENN Domain Containing 5A
Chromosome: CHR11: 9160374-9286873
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DENND5A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DENND5A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping