DENND1B FISH Probe
The DENND1B FISH probe is designed to hybridize to the DENND1B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DENND1B-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DENND1B-20-RE | 20 (40 μL) | 200 μL |  |
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| DENND1B-20-GO | 20 (40 μL) | 200 μL |  |
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| DENND1B-20-GR | 20 (40 μL) | 200 μL |  |
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| DENND1B-20-AQ | 20 (40 μL) | 200 μL |  |
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| DENND1B-20-DIG | 20 (40 μL) | 200 μL |  |
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| DENND1B-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1B, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
Gene Details
Gene Symbol: DENND1B
Gene Name: DENN Domain Containing 1B
Chromosome: CHR1: 197473878-197744623
Locus: 1q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DENND1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DENND1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping