DENND1A Break Apart FISH Probe
Empire Genomics’ DENND1A Break Apart FISH Probe is designed to flank the DENND1A gene and is typically used for detecting DENND1A rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DENND1ABA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-AQOR | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-GOGR | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-GORE | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-GRGO | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-GRRE | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-ORGR | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-REGO | 20 (40 μL) | 200 μL |
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| DENND1ABA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]).[supplied by OMIM, Nov 2010]
Gene Details
Gene Symbol: DENND1A
Gene Name: DENN Domain Containing 1A
Chromosome: CHR9: 126141932-126692417
Locus: 9q33.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DENND1A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DENND1A-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping