DEFA1B Break Apart FISH Probe
Empire Genomics’ DEFA1B Break Apart FISH Probe is designed to flank the DEFA1B gene and is typically used for detecting DEFA1B rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DEFA1BBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-AQOR | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-GOGR | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-GORE | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-GRGO | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-GRRE | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-ORGR | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-REGO | 20 (40 μL) | 200 μL |
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| DEFA1BBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 3 by only one amino acid. This gene and the gene encoding defensin, alpha 3 are both subject to copy number variation. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: DEFA1B
Gene Name: Defensin Alpha 1B
Chromosome: CHR8: 6835170-6837614
Locus: 8p23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DEFA1B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DEFA1B-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping