DDX3 FISH Probe
The DDX3 FISH probe is designed to hybridize to the DDX3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DDX3X-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DDX3X-20-RE | 20 (40 μL) | 200 μL |  |
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| DDX3X-20-GO | 20 (40 μL) | 200 μL |  |
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| DDX3X-20-GR | 20 (40 μL) | 200 μL |  |
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| DDX3X-20-AQ | 20 (40 μL) | 200 μL |  |
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| DDX3X-20-DIG | 20 (40 μL) | 200 μL |  |
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| DDX3X-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is a member of the large DEAD-box protein family, that is defined by the presence of the conserved Asp-Glu-Ala-Asp (DEAD) motif, and has ATP-dependent RNA helicase activity. This protein has been reported to display a high level of RNA-independent ATPase activity, and unlike most DEAD-box helicases, the ATPase activity is thought to be stimulated by both RNA and DNA. This protein has multiple conserved domains and is thought to play roles in both the nucleus and cytoplasm. Nuclear roles include transcriptional regulation, mRNP assembly, pre-mRNA splicing, and mRNA export. In the cytoplasm, this protein is thought to be involved in translation, cellular signaling, and viral replication. Misregulation of this gene has been implicated in tumorigenesis. This gene has a paralog located in the nonrecombining region of the Y chromosome. Pseudogenes sharing similarity to both this gene and the DDX3Y paralog are found on chromosome 4 and the X chromosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Gene Details
Gene Symbol: DDX3X
Gene Name: DEAD-box Helicase 3, X-linked
Chromosome: CHRX: 41192650-41209524
Locus: Xp11.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DDX3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DDX3X-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping