DDBB FISH Probe
The DDBB FISH probe is designed to hybridize to the DDBB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DDB2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DDB2-20-RE | 20 (40 μL) | 200 μL |  |
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| DDB2-20-GO | 20 (40 μL) | 200 μL |  |
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| DDB2-20-GR | 20 (40 μL) | 200 μL |  |
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| DDB2-20-AQ | 20 (40 μL) | 200 μL |  |
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| DDB2-20-DIG | 20 (40 μL) | 200 μL |  |
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| DDB2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a protein that is necessary for the repair of ultraviolet light-damaged DNA. This protein is the smaller subunit of a heterodimeric protein complex that participates in nucleotide excision repair, and this complex mediates the ubiquitylation of histones H3 and H4, which facilitates the cellular response to DNA damage. This subunit appears to be required for DNA binding. Mutations in this gene cause xeroderma pigmentosum complementation group E, a recessive disease that is characterized by an increased sensitivity to UV light and a high predisposition for skin cancer development, in some cases accompanied by neurological abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Gene Details
Gene Symbol: DDB2
Gene Name: Damage Specific DNA Binding Protein 2
Chromosome: CHR11: 47236492-47260769
Locus: 11p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DDBB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DDB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping