DCTN-50 FISH Probe
The DCTN-50 FISH probe is designed to hybridize to the DCTN-50 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DCTN2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DCTN2-20-RE | 20 (40 μL) | 200 μL |  |
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| DCTN2-20-GO | 20 (40 μL) | 200 μL |  |
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| DCTN2-20-GR | 20 (40 μL) | 200 μL |  |
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| DCTN2-20-AQ | 20 (40 μL) | 200 μL |  |
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| DCTN2-20-DIG | 20 (40 μL) | 200 μL |  |
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| DCTN2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a 50-kD subunit of dynactin, a macromolecular complex consisting of 10-11 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. It is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit is present in 4-5 copies per dynactin molecule. It contains three short alpha-helical coiled-coil domains that may mediate association with self or other dynactin subunits. It may interact directly with the largest subunit (p150) of dynactin and may affix p150 in place. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, May 2012]
Gene Details
Gene Symbol: DCTN2
Gene Name: Dynactin Subunit 2
Chromosome: CHR12: 57924093-57940978
Locus: 12q13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DCTN-50 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DCTN2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping