DCLK2 Break Apart FISH Probe
Empire Genomics’ DCLK2 Break Apart FISH Probe is designed to flank the DCLK2 gene and is typically used for detecting DCLK2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| DCLK2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-GORE | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-GROR | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-REGO | 20 (40 μL) | 200 μL |
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| DCLK2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of the protein kinase superfamily and the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C-terminal serine/threonine protein kinase domain, which shows substantial homology to Ca2+/calmodulin-dependent protein kinase, and a serine/proline-rich domain in between the doublecortin and the protein kinase domains, which mediates multiple protein-protein interactions. The microtubule-polymerizing activity of the encoded protein is independent of its protein kinase activity. Mouse studies show that the DCX gene, another family member, and this gene share function in the establishment of hippocampal organization and that their absence results in a severe epileptic phenotype and lethality, as described in human patients with lissencephaly. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: DCLK2
Gene Name: Doublecortin Like Kinase 2
Chromosome: CHR4: 150999425-151178608
Locus: 4q31.23-q31.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DCLK2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DCLK2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping