DCDC4B FISH Probe
The DCDC4B FISH probe is designed to hybridize to the DCDC4B gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RP1L1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RP1L1-20-RE | 20 (40 μL) | 200 μL |  |
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| RP1L1-20-GO | 20 (40 μL) | 200 μL |  |
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| RP1L1-20-GR | 20 (40 μL) | 200 μL |  |
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| RP1L1-20-AQ | 20 (40 μL) | 200 μL |  |
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| RP1L1-20-DIG | 20 (40 μL) | 200 μL |  |
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| RP1L1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the doublecortin family. The protein encoded by this gene contains two N-terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, and two C-terminal large repetitive regions, both of which contain a high percentage of glutamine and glutamic acid residues. This protein is a retinal-specific protein. Its exact length varies among individuals due to the presence of a 16aa repeat in the first C-terminal repetitive region. The 16aa repeat is encoded by the highly polymorphic 48-bp repeat, and 1-6 copies of the 16aa repeat have been identified in normal individuals. The current reference sequence shown here has a single copy of the 16aa repeat. This protein and the RP1 protein, another retinal-specific protein, play essential and synergistic roles in affecting photosensitivity and outer segment morphogenesis of rod photoreceptors. Mutations in this gene cause occult macular dystrophy (OMD). [provided by RefSeq, Sep 2010]
Gene Details
Gene Symbol: RP1L1
Gene Name: RP1 Like 1
Chromosome: CHR8: 10463859-10512617
Locus: 8p23.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DCDC4B FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RP1L1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping