DBI FISH Probe
The DBI FISH probe is designed to hybridize to the DBI gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DBI-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DBI-20-RE | 20 (40 μL) | 200 μL |  |
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| DBI-20-GO | 20 (40 μL) | 200 μL |  |
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| DBI-20-GR | 20 (40 μL) | 200 μL |  |
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| DBI-20-AQ | 20 (40 μL) | 200 μL |  |
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| DBI-20-DIG | 20 (40 μL) | 200 μL |  |
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| DBI-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes diazepam binding inhibitor, a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: DBI
Gene Name: Diazepam Binding Inhibitor, Acyl-CoA Binding Protein
Chromosome: CHR2: 120124503-120130122
Locus: 2q14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DBI FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DBI-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping