DBA FISH Probe
The DBA FISH probe is designed to hybridize to the DBA gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RPS19-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RPS19-20-RE | 20 (40 μL) | 200 μL |  |
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| RPS19-20-GO | 20 (40 μL) | 200 μL |  |
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| RPS19-20-GR | 20 (40 μL) | 200 μL |  |
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| RPS19-20-AQ | 20 (40 μL) | 200 μL |  |
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| RPS19-20-DIG | 20 (40 μL) | 200 μL |  |
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| RPS19-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S19E family of ribosomal proteins. It is located in the cytoplasm. Mutations in this gene cause Diamond-Blackfan anemia (DBA), a constitutional erythroblastopenia characterized by absent or decreased erythroid precursors, in a subset of patients. This suggests a possible extra-ribosomal function for this gene in erythropoietic differentiation and proliferation, in addition to its ribosomal function. Higher expression levels of this gene in some primary colon carcinomas compared to matched normal colon tissues has been observed. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RPS19
Gene Name: Ribosomal Protein S19
Chromosome: CHR19: 42363987-42375484
Locus: 19q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DBA FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RPS19-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping