DAXX FISH Probe
The DAXX FISH probe is designed to hybridize to the DAXX gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DAXX-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DAXX-20-RE | 20 (40 μL) | 200 μL |  |
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| DAXX-20-GO | 20 (40 μL) | 200 μL |  |
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| DAXX-20-GR | 20 (40 μL) | 200 μL |  |
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| DAXX-20-AQ | 20 (40 μL) | 200 μL |  |
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| DAXX-20-DIG | 20 (40 μL) | 200 μL |  |
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| DAXX-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a multifunctional protein that resides in multiple locations in the nucleus and in the cytoplasm. It interacts with a wide variety of proteins, such as apoptosis antigen Fas, centromere protein C, and transcription factor erythroblastosis virus E26 oncogene homolog 1. In the nucleus, the encoded protein functions as a potent transcription repressor that binds to sumoylated transcription factors. Its repression can be relieved by the sequestration of this protein into promyelocytic leukemia nuclear bodies or nucleoli. This protein also associates with centromeres in G2 phase. In the cytoplasm, the encoded protein may function to regulate apoptosis. The subcellular localization and function of this protein are modulated by post-translational modifications, including sumoylation, phosphorylation and polyubiquitination. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2008]
Gene Details
Gene Symbol: DAXX
Gene Name: Death Domain Associated Protein
Chromosome: CHR6_cox_hap2: 4730148-4734611
Locus: 6p21.32
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DAXX FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DAXX-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping