DAP3 FISH Probe
The DAP3 FISH probe is designed to hybridize to the DAP3 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| DAP3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| DAP3-20-RE | 20 (40 μL) | 200 μL |  |
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| DAP3-20-GO | 20 (40 μL) | 200 μL |  |
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| DAP3-20-GR | 20 (40 μL) | 200 μL |  |
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| DAP3-20-AQ | 20 (40 μL) | 200 μL |  |
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| DAP3-20-DIG | 20 (40 μL) | 200 μL |  |
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| DAP3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein that also participates in apoptotic pathways which are initiated by tumor necrosis factor-alpha, Fas ligand, and gamma interferon. This protein potentially binds ATP/GTP and might be a functional partner of the mitoribosomal protein S27. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. Pseudogenes corresponding to this gene are found on chromosomes 1q and 2q. [provided by RefSeq, Dec 2010]
Gene Details
Gene Symbol: DAP3
Gene Name: Death Associated Protein 3
Chromosome: CHR1: 155658881-155708800
Locus: 1q22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DAP3 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: DAP3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping