DAP-5 FISH Probe
The DAP-5 FISH probe is designed to hybridize to the DAP-5 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| EIF4G2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| EIF4G2-20-RE | 20 (40 μL) | 200 μL |  |
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| EIF4G2-20-GO | 20 (40 μL) | 200 μL |  |
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| EIF4G2-20-GR | 20 (40 μL) | 200 μL |  |
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| EIF4G2-20-AQ | 20 (40 μL) | 200 μL |  |
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| EIF4G2-20-DIG | 20 (40 μL) | 200 μL |  |
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| EIF4G2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Translation initiation is mediated by specific recognition of the cap structure by eukaryotic translation initiation factor 4F (eIF4F), which is a cap binding protein complex that consists of three subunits: eIF4A, eIF4E and eIF4G. The protein encoded by this gene shares similarity with the C-terminal region of eIF4G that contains the binding sites for eIF4A and eIF3; eIF4G, in addition, contains a binding site for eIF4E at the N-terminus. Unlike eIF4G, which supports cap-dependent and independent translation, this gene product functions as a general repressor of translation by forming translationally inactive complexes. In vitro and in vivo studies indicate that translation of this mRNA initiates exclusively at a non-AUG (GUG) codon. Alternatively spliced transcript variants encoding different isoforms of this gene have been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: EIF4G2
Gene Name: Eukaryotic Translation Initiation Factor 4 Gamma 2
Chromosome: CHR11: 10818592-10830582
Locus: 11p15.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: DAP-5 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: EIF4G2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping