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DAP-150 FISH Probe

The DAP-150 FISH probe is designed to hybridize to the DAP-150 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
DCTN1-20-OR  (Standard Design) 20 (40 μL) 200 μL
DCTN1-20-RE 20 (40 μL) 200 μL
DCTN1-20-GO 20 (40 μL) 200 μL
DCTN1-20-GR 20 (40 μL) 200 μL
DCTN1-20-AQ 20 (40 μL) 200 μL
DCTN1-20-DIG 20 (40 μL) 200 μL
DCTN1-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. This subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. Mutations in this gene cause distal hereditary motor neuronopathy type VIIB (HMN7B) which is also known as distal spinal and bulbar muscular atrophy (dSBMA). [provided by RefSeq, Oct 2008]

Gene Details

Gene Symbol: DCTN1

Gene Name: Dynactin Subunit 1

Chromosome: CHR2: 74588280-74619214

Locus: 2p13.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DAP-150 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DCTN1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping