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DAB2 FISH Probe

The DAB2 FISH probe is designed to hybridize to the DAB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

SKU Test Kits Buffer Dye Color Order Now
DAB2-20-OR  (Standard Design) 20 (40 μL) 200 μL
DAB2-20-RE 20 (40 μL) 200 μL
DAB2-20-GO 20 (40 μL) 200 μL
DAB2-20-GR 20 (40 μL) 200 μL
DAB2-20-AQ 20 (40 μL) 200 μL
DAB2-20-DIG 20 (40 μL) 200 μL
DAB2-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a mitogen-responsive phosphoprotein. It is expressed in normal ovarian epithelial cells, but is down-regulated or absent from ovarian carcinoma cell lines, suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2, an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras), via its C-terminal proline-rich sequences, and may thus modulate growth factor/Ras pathways by competing with SOS for binding to GRB2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

Gene Details

Gene Symbol: DAB2

Gene Name: DAB2, Clathrin Adaptor Protein

Chromosome: CHR5: 39371779-39425335

Locus: 5p13.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: DAB2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: DAB2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping