D60 FISH Probe
The D60 FISH probe is designed to hybridize to the D60 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MRPS31-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MRPS31-20-RE | 20 (40 μL) | 200 μL |  |
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| MRPS31-20-GO | 20 (40 μL) | 200 μL |  |
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| MRPS31-20-GR | 20 (40 μL) | 200 μL |  |
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| MRPS31-20-AQ | 20 (40 μL) | 200 μL |  |
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| MRPS31-20-DIG | 20 (40 μL) | 200 μL |  |
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| MRPS31-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MRPS31
Gene Name: Mitochondrial Ribosomal Protein S31
Chromosome: CHR13: 41303431-41345347
Locus: 13q14.11
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D60 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MRPS31-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping