D1S2223E FISH Probe
The D1S2223E FISH probe is designed to hybridize to the D1S2223E gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PEX19-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| PEX19-20-RE | 20 (40 μL) | 200 μL |  |
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| PEX19-20-GO | 20 (40 μL) | 200 μL |  |
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| PEX19-20-GR | 20 (40 μL) | 200 μL |  |
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| PEX19-20-AQ | 20 (40 μL) | 200 μL |  |
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| PEX19-20-DIG | 20 (40 μL) | 200 μL |  |
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| PEX19-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is necessary for early peroxisomal biogenesis. It acts both as a cytosolic chaperone and as an import receptor for peroxisomal membrane proteins (PMPs). Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. These disorders have at least 14 complementation groups, with more than one phenotype being observed for some complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause of Zellweger syndrome (ZWS), as well as peroxisome biogenesis disorder complementation group 14 (PBD-CG14), which is also known as PBD-CGJ. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2010]
Gene Details
Gene Symbol: PEX19
Gene Name: Peroxisomal Biogenesis Factor 19
Chromosome: CHR1: 160246598-160254941
Locus: 1q23.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D1S2223E FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: PEX19-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping