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D18386 FISH Probe

The D18386 FISH probe is designed to hybridize to the D18386 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
SAFB-20-OR  (Standard Design) 20 (40 μL) 200 μL
SAFB-20-RE 20 (40 μL) 200 μL
SAFB-20-GO 20 (40 μL) 200 μL
SAFB-20-GR 20 (40 μL) 200 μL
SAFB-20-AQ 20 (40 μL) 200 μL
SAFB-20-DIG 20 (40 μL) 200 μL
SAFB-20-BIO 20 (40 μL) 200 μL

Gene Summary

This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements (S/MAR DNA). This protein is thought to be involved in attaching the base of chromatin loops to the nuclear matrix but there is conflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein. Scaffold attachment factors are a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR. The encoded protein is thought to serve as a molecular base to assemble a 'transcriptosome complex' in the vicinity of actively transcribed genes. It is involved in the regulation of heat shock protein 27 transcription, can act as an estrogen receptor co-repressor and is a candidate for breast tumorigenesis. This gene is arranged head-to-head with a similar gene whose product has the same functions. Multiple transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jan 2011]

Gene Details

Gene Symbol: SAFB

Gene Name: Scaffold Attachment Factor B

Chromosome: CHR19: 5623045-5668489

Locus: 19p13.3

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: D18386 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: SAFB-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping