D17S1718 FISH Probe
The D17S1718 FISH probe is designed to hybridize to the D17S1718 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
SKU | Test Kits | Buffer | Dye Color | Order Now |
---|---|---|---|---|
CCL3L1-20-OR (Standard Design) | 20 (40 μL) | 200 μL | ||
CCL3L1-20-RE | 20 (40 μL) | 200 μL | ||
CCL3L1-20-GO | 20 (40 μL) | 200 μL | ||
CCL3L1-20-GR | 20 (40 μL) | 200 μL | ||
CCL3L1-20-AQ | 20 (40 μL) | 200 μL | ||
CCL3L1-20-DIG | 20 (40 μL) | 200 μL | ||
CCL3L1-20-BIO | 20 (40 μL) | 200 μL |
Gene Summary
This gene is one of several cytokine genes that are clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins that function in inflammatory and immunoregulatory processes. The protein encoded by this gene binds to several chemokine receptors, including chemokine binding protein 2 and chemokine (C-C motif) receptor 5 (CCR5). CCR5 is a co-receptor for HIV, and binding of this protein to CCR5 inhibits HIV entry. The copy number of this gene varies among individuals, where most individuals have one to six copies, and a minority of individuals have zero or more than six copies. There are conflicting reports about copy number variation of this gene and its correlation to disease susceptibility. This record represents one of two copies that are present on the ALT_REF_LOCI_2 alternate haplotype of the GRCh38 human reference genome assembly. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Details
Gene Symbol: CCL3L1
Gene Name: C-C Motif Chemokine Ligand 3 Like 1
Chromosome: CHR17: 34623841-34625730
Locus: 17q21.1
FISH Probe Protocols
Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D17S1718 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCL3L1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping