D17S136E FISH Probe
The D17S136E FISH probe is designed to hybridize to the D17S136E gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CCL5-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CCL5-20-RE | 20 (40 μL) | 200 μL |  |
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| CCL5-20-GO | 20 (40 μL) | 200 μL |  |
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| CCL5-20-GR | 20 (40 μL) | 200 μL |  |
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| CCL5-20-AQ | 20 (40 μL) | 200 μL |  |
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| CCL5-20-DIG | 20 (40 μL) | 200 μL |  |
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| CCL5-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, Jul 2013]
Gene Details
Gene Symbol: CCL5
Gene Name: C-C Motif Chemokine Ligand 5
Chromosome: CHR17: 34198495-34207377
Locus: 17q12
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D17S136E FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CCL5-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping