D17825 FISH Probe
The D17825 FISH probe is designed to hybridize to the D17825 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| GCDH-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| GCDH-20-RE | 20 (40 μL) | 200 μL |  |
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| GCDH-20-GO | 20 (40 μL) | 200 μL |  |
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| GCDH-20-GR | 20 (40 μL) | 200 μL |  |
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| GCDH-20-AQ | 20 (40 μL) | 200 μL |  |
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| GCDH-20-DIG | 20 (40 μL) | 200 μL |  |
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| GCDH-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene belongs to the acyl-CoA dehydrogenase family. It catalyzes the oxidative decarboxylation of glutaryl-CoA to crotonyl-CoA and CO(2) in the degradative pathway of L-lysine, L-hydroxylysine, and L-tryptophan metabolism. It uses electron transfer flavoprotein as its electron acceptor. The enzyme exists in the mitochondrial matrix as a homotetramer of 45-kD subunits. Mutations in this gene result in the metabolic disorder glutaric aciduria type 1, which is also known as glutaric acidemia type I. Alternative splicing of this gene results in multiple transcript variants. A related pseudogene has been identified on chromosome 12. [provided by RefSeq, Mar 2013]
Gene Details
Gene Symbol: GCDH
Gene Name: Glutaryl-CoA Dehydrogenase
Chromosome: CHR19: 13001973-13010783
Locus: 19p13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D17825 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: GCDH-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping