D10S65 FISH Probe
The D10S65 FISH probe is designed to hybridize to the D10S65 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RBP3-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| RBP3-20-RE | 20 (40 μL) | 200 μL |  |
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| RBP3-20-GO | 20 (40 μL) | 200 μL |  |
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| RBP3-20-GR | 20 (40 μL) | 200 μL |  |
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| RBP3-20-AQ | 20 (40 μL) | 200 μL |  |
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| RBP3-20-DIG | 20 (40 μL) | 200 μL |  |
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| RBP3-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Interphotoreceptor retinol-binding protein is a large glycoprotein known to bind retinoids and found primarily in the interphotoreceptor matrix of the retina between the retinal pigment epithelium and the photoreceptor cells. It is thought to transport retinoids between the retinal pigment epithelium and the photoreceptors, a critical role in the visual process.The human IRBP gene is approximately 9.5 kbp in length and consists of four exons separated by three introns. The introns are 1.6-1.9 kbp long. The gene is transcribed by photoreceptor and retinoblastoma cells into an approximately 4.3-kilobase mRNA that is translated and processed into a glycosylated protein of 135,000 Da. The amino acid sequence of human IRBP can be divided into four contiguous homology domains with 33-38% identity, suggesting a series of gene duplication events. In the gene, the boundaries of these domains are not defined by exon-intron junctions, as might have been expected. The first three homology domains and part of the fourth are all encoded by the first large exon, which is 3,180 base pairs long. The remainder of the fourth domain is encoded in the last three exons, which are 191, 143, and approximately 740 base pairs long, respectively. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: RBP3
Gene Name: Retinol Binding Protein 3
Chromosome: CHR10: 48381486-48390991
Locus: 10q11.22
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: D10S65 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: RBP3-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping