CYPIIIA21 FISH Probe
The CYPIIIA21 FISH probe is designed to hybridize to the CYPIIIA21 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP3A4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP3A4-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP3A4-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP3A4-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP3A4-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP3A4-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP3A4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases that catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. This enzyme is involved in the metabolism of approximately half the drugs in use today, including acetaminophen, codeine, cyclosporin A, diazepam and erythromycin. The enzyme also metabolizes some steroids and carcinogens. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. Previously another CYP3A gene, CYP3A3, was thought to exist; however, it is now thought that this sequence represents a transcript variant of CYP3A4. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Feb 2011]
Gene Details
Gene Symbol: CYP3A4
Gene Name: Cytochrome P450 Family 3 Subfamily A Member 4
Chromosome: CHR7: 99354582-99381811
Locus: 7q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYPIIIA21 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP3A4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping