CYPIIA6 FISH Probe
The CYPIIA6 FISH probe is designed to hybridize to the CYPIIA6 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP2A6-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CYP2A6-20-RE | 20 (40 μL) | 200 μL |  |
|
| CYP2A6-20-GO | 20 (40 μL) | 200 μL |  |
|
| CYP2A6-20-GR | 20 (40 μL) | 200 μL |  |
|
| CYP2A6-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CYP2A6-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CYP2A6-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene, CYP2A6, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by phenobarbital. The enzyme is known to hydroxylate coumarin, and also metabolizes nicotine, aflatoxin B1, nitrosamines, and some pharmaceuticals. Individuals with certain allelic variants are said to have a poor metabolizer phenotype, meaning they do not efficiently metabolize coumarin or nicotine. This gene is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. The gene was formerly referred to as CYP2A3; however, it has been renamed CYP2A6. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CYP2A6
Gene Name: Cytochrome P450 Family 2 Subfamily A Member 6
Chromosome: CHR19: 41349442-41356352
Locus: 19q13.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CYPIIA6 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP2A6-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping