CYP7B1 FISH Probe
The CYP7B1 FISH probe is designed to hybridize to the CYP7B1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP7B1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP7B1-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP7B1-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP7B1-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP7B1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP7B1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP7B1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
Gene Details
Gene Symbol: CYP7B1
Gene Name: Cytochrome P450 Family 7 Subfamily B Member 1
Chromosome: CHR8: 65508528-65711348
Locus: 8q12.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYP7B1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP7B1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping