CYP46A1 FISH Probe
The CYP46A1 FISH probe is designed to hybridize to the CYP46A1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP46A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CYP46A1-20-RE | 20 (40 μL) | 200 μL |  |
|
| CYP46A1-20-GO | 20 (40 μL) | 200 μL |  |
|
| CYP46A1-20-GR | 20 (40 μL) | 200 μL |  |
|
| CYP46A1-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CYP46A1-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CYP46A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein is expressed in the brain, where it converts cholesterol to 24S-hydroxycholesterol. While cholesterol cannot pass the blood-brain barrier, 24S-hydroxycholesterol can be secreted in the brain into the circulation to be returned to the liver for catabolism. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CYP46A1
Gene Name: Cytochrome P450 Family 46 Subfamily A Member 1
Chromosome: CHR14: 100150754-100193638
Locus: 14q32.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CYP46A1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP46A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping