CYP2C19 FISH Probe
The CYP2C19 FISH probe is designed to hybridize to the CYP2C19 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP2C19-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP2C19-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP2C19-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP2C19-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP2C19-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP2C19-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP2C19-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize many xenobiotics, including the anticonvulsive drug mephenytoin, omeprazole, diazepam and some barbiturates. Polymorphism within this gene is associated with variable ability to metabolize mephenytoin, known as the poor metabolizer and extensive metabolizer phenotypes. The gene is located within a cluster of cytochrome P450 genes on chromosome 10q24. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CYP2C19
Gene Name: Cytochrome P450 Family 2 Subfamily C Member 19
Chromosome: CHR10: 96522462-96612671
Locus: 10q23.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYP2C19 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP2C19-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping