CYP21A FISH Probe
The CYP21A FISH probe is designed to hybridize to the CYP21A gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP21A2-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP21A2-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP21A2-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP21A2-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP21A2-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP21A2-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP21A2-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates steroids at the 21 position. Its activity is required for the synthesis of steroid hormones including cortisol and aldosterone. Mutations in this gene cause congenital adrenal hyperplasia. A related pseudogene is located near this gene; gene conversion events involving the functional gene and the pseudogene are thought to account for many cases of steroid 21-hydroxylase deficiency. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CYP21A2
Gene Name: Cytochrome P450 Family 21 Subfamily A Member 2
Chromosome: CHR6_ssto_hap7: 3306068-3342155
Locus: 6p21.33
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYP21A FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP21A2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping