CYP1A4 FISH Probe
The CYP1A4 FISH probe is designed to hybridize to the CYP1A4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYP1A1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CYP1A1-20-RE | 20 (40 μL) | 200 μL |  |
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| CYP1A1-20-GO | 20 (40 μL) | 200 μL |  |
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| CYP1A1-20-GR | 20 (40 μL) | 200 μL |  |
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| CYP1A1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CYP1A1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CYP1A1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons (PAHs), some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jan 2016]
Gene Details
Gene Symbol: CYP1A1
Gene Name: Cytochrome P450 Family 1 Subfamily A Member 1
Chromosome: CHR15: 75011882-75017877
Locus: 15q24.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CYP1A4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYP1A1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping