CYBB FISH Probe
The CYBB FISH probe is designed to hybridize to the CYBB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CYBB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
|
| CYBB-20-RE | 20 (40 μL) | 200 μL |  |
|
| CYBB-20-GO | 20 (40 μL) | 200 μL |  |
|
| CYBB-20-GR | 20 (40 μL) | 200 μL |  |
|
| CYBB-20-AQ | 20 (40 μL) | 200 μL |  |
|
| CYBB-20-DIG | 20 (40 μL) | 200 μL |  |
|
| CYBB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Cytochrome b (-245) is composed of cytochrome b alpha (CYBA) and beta (CYBB) chain. It has been proposed as a primary component of the microbicidal oxidase system of phagocytes. CYBB deficiency is one of five described biochemical defects associated with chronic granulomatous disease (CGD). In this disorder, there is decreased activity of phagocyte NADPH oxidase; neutrophils are able to phagocytize bacteria but cannot kill them in the phagocytic vacuoles. The cause of the killing defect is an inability to increase the cell's respiration and consequent failure to deliver activated oxygen into the phagocytic vacuole. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CYBB
Gene Name: Cytochrome B-245 Beta Chain
Chromosome: CHRX: 37639269-37672714
Locus: Xp21.1-p11.4
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|
Customer Publications
Product Details
Product: CYBB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CYBB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping