CTSC FISH Probe
The CTSC FISH probe is designed to hybridize to the CTSC gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTSC-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTSC-20-RE | 20 (40 μL) | 200 μL |  |
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| CTSC-20-GO | 20 (40 μL) | 200 μL |  |
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| CTSC-20-GR | 20 (40 μL) | 200 μL |  |
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| CTSC-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTSC-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTSC-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes a member of the peptidase C1 family and lysosomal cysteine proteinase that appears to be a central coordinator for activation of many serine proteinases in cells of the immune system. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate heavy and light chains that form a disulfide-linked dimer. A portion of the propeptide acts as an intramolecular chaperone for the folding and stabilization of the mature enzyme. This enzyme requires chloride ions for activity and can degrade glucagon. Defects in the encoded protein have been shown to be a cause of Papillon-Lefevre syndrome, an autosomal recessive disorder characterized by palmoplantar keratosis and periodontitis. [provided by RefSeq, Nov 2015]
Gene Details
Gene Symbol: CTSC
Gene Name: Cathepsin C
Chromosome: CHR11: 88026759-88070941
Locus: 11q14.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CTSC FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTSC-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping