CTNNB1 FISH Probe
The CTNNB1 FISH probe is designed to hybridize to the CTNNB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTNNB1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTNNB1-20-RE | 20 (40 μL) | 200 μL |  |
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| CTNNB1-20-GO | 20 (40 μL) | 200 μL |  |
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| CTNNB1-20-GR | 20 (40 μL) | 200 μL |  |
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| CTNNB1-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTNNB1-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTNNB1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2016]
Gene Details
Gene Symbol: CTNNB1
Gene Name: Catenin Beta 1
Chromosome: CHR3: 41240941-41281939
Locus: 3p22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CTNNB1 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTNNB1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping