CTLA4 FISH Probe
The CTLA4 FISH probe is designed to hybridize to the CTLA4 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTLA4-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTLA4-20-RE | 20 (40 μL) | 200 μL |  |
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| CTLA4-20-GO | 20 (40 μL) | 200 μL |  |
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| CTLA4-20-GR | 20 (40 μL) | 200 μL |  |
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| CTLA4-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTLA4-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTLA4-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene is a member of the immunoglobulin superfamily and encodes a protein which transmits an inhibitory signal to T cells. The protein contains a V domain, a transmembrane domain, and a cytoplasmic tail. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. The membrane-bound isoform functions as a homodimer interconnected by a disulfide bond, while the soluble isoform functions as a monomer. Mutations in this gene have been associated with insulin-dependent diabetes mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune diseases. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CTLA4
Gene Name: Cytotoxic T-lymphocyte Associated Protein 4
Chromosome: CHR2: 204732510-204738683
Locus: 2q33.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CTLA4 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTLA4-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping