CTIF Break Apart FISH Probe
Empire Genomics’ CTIF Break Apart FISH Probe is designed to flank the CTIF gene and is typically used for detecting CTIF rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTIFBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTIFBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CTIFBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CTIFBA-20-GORE | 20 (40 μL) | 200 μL |
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| CTIFBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CTIFBA-20-GROR | 20 (40 μL) | 200 μL |
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| CTIFBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CTIFBA-20-REGO | 20 (40 μL) | 200 μL |
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| CTIFBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]
Gene Details
Gene Symbol: CTIF
Gene Name: Cap Binding Complex Dependent Translation Initiation Factor
Chromosome: CHR18: 46065426-46389586
Locus: 18q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CTIF FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTIF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping