CTIF FISH Probe
The CTIF FISH probe is designed to hybridize to the CTIF gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CTIF-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CTIF-20-RE | 20 (40 μL) | 200 μL |  |
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| CTIF-20-GO | 20 (40 μL) | 200 μL |  |
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| CTIF-20-GR | 20 (40 μL) | 200 μL |  |
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| CTIF-20-AQ | 20 (40 μL) | 200 μL |  |
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| CTIF-20-DIG | 20 (40 μL) | 200 μL |  |
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| CTIF-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
CTIF is a component of the CBP80 (NCBP1; MIM 600469)/CBP20 (NCBP2; MIM 605133) translation initiation complex that binds cotranscriptionally to the cap end of nascent mRNA. The CBP80/CBP20 complex is involved in a simultaneous editing and translation step that recognizes premature termination codons (PTCs) in mRNAs and directs PTC-containing mRNAs toward nonsense-mediated decay (NMD). On mRNAs without PTCs, the CBP80/CBP20 complex is replaced with cytoplasmic mRNA cap-binding proteins, including EIF4G (MIM 600495), and steady-state translation of the mRNAs resumes in the cytoplasm (Kim et al., 2009 [PubMed 19648179]).[supplied by OMIM, Dec 2009]
Gene Details
Gene Symbol: CTIF
Gene Name: Cap Binding Complex Dependent Translation Initiation Factor
Chromosome: CHR18: 46065426-46389586
Locus: 18q21.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CTIF FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTIF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping