CTCF Break Apart FISH Probe
Empire Genomics’ CTCF Break Apart FISH Probe is designed to flank the CTCF gene and is typically used for detecting CTCF rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CTCFBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CTCFBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CTCFBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CTCFBA-20-GORE | 20 (40 μL) | 200 μL |
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| CTCFBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CTCFBA-20-GROR | 20 (40 μL) | 200 μL |
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| CTCFBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CTCFBA-20-REGO | 20 (40 μL) | 200 μL |
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| CTCFBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Gene Details
Gene Symbol: CTCF
Gene Name: CCCTC-binding Factor
Chromosome: CHR16: 67596309-67673088
Locus: 16q22.1
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CTCF FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CTCF-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping