CSTB Break Apart FISH Probe
Empire Genomics’ CSTB Break Apart FISH Probe is designed to flank the CSTB gene and is typically used for detecting CSTB rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSTBBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSTBBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CSTBBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CSTBBA-20-GORE | 20 (40 μL) | 200 μL |
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| CSTBBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CSTBBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CSTBBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CSTBBA-20-REGO | 20 (40 μL) | 200 μL |
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| CSTBBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies. [provided by RefSeq, Jul 2016]
Gene Details
Gene Symbol: CSTB
Gene Name: Cystatin B
Chromosome: CHR21: 45193830-45196259
Locus: 21q22.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CSTB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CSTB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping