CSKL FISH Probe
The CSKL FISH probe is designed to hybridize to the CSKL gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| MATK-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| MATK-20-RE | 20 (40 μL) | 200 μL |  |
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| MATK-20-GO | 20 (40 μL) | 200 μL |  |
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| MATK-20-GR | 20 (40 μL) | 200 μL |  |
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| MATK-20-AQ | 20 (40 μL) | 200 μL |  |
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| MATK-20-DIG | 20 (40 μL) | 200 μL |  |
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| MATK-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. This protein is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. Three alternatively spliced transcript variants that encode different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: MATK
Gene Name: Megakaryocyte-associated Tyrosine Kinase
Chromosome: CHR19: 3777966-3801810
Locus: 19p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CSKL FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: MATK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping