CSHMT FISH Probe
The CSHMT FISH probe is designed to hybridize to the CSHMT gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| SHMT1-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| SHMT1-20-RE | 20 (40 μL) | 200 μL |  |
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| SHMT1-20-GO | 20 (40 μL) | 200 μL |  |
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| SHMT1-20-GR | 20 (40 μL) | 200 μL |  |
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| SHMT1-20-AQ | 20 (40 μL) | 200 μL |  |
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| SHMT1-20-DIG | 20 (40 μL) | 200 μL |  |
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| SHMT1-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
This gene encodes the cytosolic form of serine hydroxymethyltransferase, a pyridoxal phosphate-containing enzyme that catalyzes the reversible conversion of serine and tetrahydrofolate to glycine and 5,10-methylene tetrahydrofolate. This reaction provides one-carbon units for synthesis of methionine, thymidylate, and purines in the cytoplasm. This gene is located within the Smith-Magenis syndrome region on chromosome 17. A pseudogene of this gene is located on the short arm of chromosome 1. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Gene Details
Gene Symbol: SHMT1
Gene Name: Serine Hydroxymethyltransferase 1
Chromosome: CHR17: 18231186-18266856
Locus: 17p11.2
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CSHMT FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: SHMT1-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping