CSE1L Break Apart FISH Probe
Empire Genomics’ CSE1L Break Apart FISH Probe is designed to flank the CSE1L gene and is typically used for detecting CSE1L rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CSE1LBA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-GORE | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-GROR | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-REGO | 20 (40 μL) | 200 μL |
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| CSE1LBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Details
Gene Symbol: CSE1L
Gene Name: Chromosome Segregation 1 Like
Chromosome: CHR20: 47662837-47713486
Locus: 20q13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CSE1L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CSE1L-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping