CSE1L FISH Probe
The CSE1L FISH probe is designed to hybridize to the CSE1L gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CSE1L-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CSE1L-20-RE | 20 (40 μL) | 200 μL |  |
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| CSE1L-20-GO | 20 (40 μL) | 200 μL |  |
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| CSE1L-20-GR | 20 (40 μL) | 200 μL |  |
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| CSE1L-20-AQ | 20 (40 μL) | 200 μL |  |
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| CSE1L-20-DIG | 20 (40 μL) | 200 μL |  |
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| CSE1L-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Proteins that carry a nuclear localization signal (NLS) are transported into the nucleus by the importin-alpha/beta heterodimer. Importin-alpha binds the NLS, while importin-beta mediates translocation through the nuclear pore complex. After translocation, RanGTP binds importin-beta and displaces importin-alpha. Importin-alpha must then be returned to the cytoplasm, leaving the NLS protein behind. The protein encoded by this gene binds strongly to NLS-free importin-alpha, and this binding is released in the cytoplasm by the combined action of RANBP1 and RANGAP1. In addition, the encoded protein may play a role both in apoptosis and in cell proliferation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
Gene Details
Gene Symbol: CSE1L
Gene Name: Chromosome Segregation 1 Like
Chromosome: CHR20: 47662837-47713486
Locus: 20q13.13
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CSE1L FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CSE1L-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping