CRYGB FISH Probe
The CRYGB FISH probe is designed to hybridize to the CRYGB gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| CRYGB-20-OR (Standard Design) | 20 (40 μL) | 200 μL |  |
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| CRYGB-20-RE | 20 (40 μL) | 200 μL |  |
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| CRYGB-20-GO | 20 (40 μL) | 200 μL |  |
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| CRYGB-20-GR | 20 (40 μL) | 200 μL |  |
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| CRYGB-20-AQ | 20 (40 μL) | 200 μL |  |
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| CRYGB-20-DIG | 20 (40 μL) | 200 μL |  |
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| CRYGB-20-BIO | 20 (40 μL) | 200 μL |  |
Gene Summary
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Gamma-crystallins are a homogeneous group of highly symmetrical, monomeric proteins typically lacking connecting peptides and terminal extensions. They are differentially regulated after early development. Four gamma-crystallin genes (gamma-A through gamma-D) and three pseudogenes (gamma-E, gamma-F, gamma-G) are tandemly organized in a genomic segment as a gene cluster. Whether due to aging or mutations in specific genes, gamma-crystallins have been involved in cataract formation. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CRYGB
Gene Name: Crystallin Gamma B
Chromosome: CHR2: 209007296-209010877
Locus: 2q33.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CRYGB FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CRYGB-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping