CRYBB2 Break Apart FISH Probe
Empire Genomics’ CRYBB2 Break Apart FISH Probe is designed to flank the CRYBB2 gene and is typically used for detecting CRYBB2 rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in orange and green by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRYBB2BA-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-AQOR | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-GOGR | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-GORE | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-GRGO | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-GROR | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-GRRE | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-REGO | 20 (40 μL) | 200 μL |
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| CRYBB2BA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CRYBB2
Gene Name: Crystallin Beta B2
Chromosome: CHR22: 25615611-25627836
Locus: 22q11.23
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CRYBB2 FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CRYBB2-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping