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CRYBB2 FISH Probe

The CRYBB2 FISH probe is designed to hybridize to the CRYBB2 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CRYBB2-20-OR  (Standard Design) 20 (40 μL) 200 μL
CRYBB2-20-RE 20 (40 μL) 200 μL
CRYBB2-20-GO 20 (40 μL) 200 μL
CRYBB2-20-GR 20 (40 μL) 200 μL
CRYBB2-20-AQ 20 (40 μL) 200 μL
CRYBB2-20-DIG 20 (40 μL) 200 μL
CRYBB2-20-BIO 20 (40 μL) 200 μL

Gene Summary

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, is part of a gene cluster with beta-A4, beta-B1, and beta-B3. A chain-terminating mutation was found to cause type 2 cerulean cataracts. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CRYBB2

Gene Name: Crystallin Beta B2

Chromosome: CHR22: 25615611-25627836

Locus: 22q11.23

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CRYBB2 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CRYBB2-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping