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CRYB1 FISH Probe

The CRYB1 FISH probe is designed to hybridize to the CRYB1 gene and is primarily used for detecting amplifications and deletions associated with the gene. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe can be labeled in one of five colors. Each probe is sold in a 20 test kit (approximately 20 slides - 22x22 mm area) and includes hybridization buffer. Please note that due to design optimizations, prices are subject to change.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
CRYBB1-20-OR  (Standard Design) 20 (40 μL) 200 μL
CRYBB1-20-RE 20 (40 μL) 200 μL
CRYBB1-20-GO 20 (40 μL) 200 μL
CRYBB1-20-GR 20 (40 μL) 200 μL
CRYBB1-20-AQ 20 (40 μL) 200 μL
CRYBB1-20-DIG 20 (40 μL) 200 μL
CRYBB1-20-BIO 20 (40 μL) 200 μL

Gene Summary

Crystallins are separated into two classes: taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Beta-crystallins, the most heterogeneous, differ by the presence of the C-terminal extension (present in the basic group, none in the acidic group). Beta-crystallins form aggregates of different sizes and are able to self-associate to form dimers or to form heterodimers with other beta-crystallins. This gene, a beta basic group member, undergoes extensive cleavage at its N-terminal extension during lens maturation. It is also a member of a gene cluster with beta-A4, beta-B2, and beta-B3. [provided by RefSeq, Jul 2008]

Gene Details

Gene Symbol: CRYBB1

Gene Name: Crystallin Beta B1

Chromosome: CHR22: 26995361-27013991

Locus: 22q12.1

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this gene.

Product Details

Product: CRYB1 FISH Probe

Test Kits: 20 (40 μL)

ISH Buffer: 200 μL

SKU: CRYBB1-20-OR

Material Safety Data Sheet: MSDS.pdf

Turnaround Time: 7-10 Business Days

Shipping Time: 1-2 Day Expedited Shipping