CRK Break Apart FISH Probe
Empire Genomics’ CRK Break Apart FISH Probe is designed to flank the CRK gene and is typically used for detecting CRK rearrangements such as translocations. This probe is FISH confirmed on normal peripheral blood metaphase spreads and interphase nuclei. The probe comes labeled in green and orange by default, but may be customized to meet your needs.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| CRKBA-20-GROR (Standard Design) | 20 (40 μL) | 200 μL |
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| CRKBA-20-AQOR | 20 (40 μL) | 200 μL |
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| CRKBA-20-GOGR | 20 (40 μL) | 200 μL |
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| CRKBA-20-GORE | 20 (40 μL) | 200 μL |
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| CRKBA-20-GRGO | 20 (40 μL) | 200 μL |
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| CRKBA-20-GRRE | 20 (40 μL) | 200 μL |
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| CRKBA-20-ORGR | 20 (40 μL) | 200 μL |
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| CRKBA-20-REGO | 20 (40 μL) | 200 μL |
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| CRKBA-20-REGR | 20 (40 μL) | 200 μL |
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Gene Summary
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described. [provided by RefSeq, Jul 2008]
Gene Details
Gene Symbol: CRK
Gene Name: CRK Proto-oncogene, Adaptor Protein
Chromosome: CHR17: 1325457-1359544
Locus: 17p13.3
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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Customer Publications
Product Details
Product: CRK FISH Probe
Test Kits: 20 (40 μL)
ISH Buffer: 200 μL
SKU: CRK-20-OR
Material Safety Data Sheet: MSDS.pdf
Turnaround Time: 7-10 Business Days
Shipping Time: 1-2 Day Expedited Shipping